Flumazenil Impurity 11 CAS 1248271-71-7 (free acid)
| CAS No. | 1248271-71-7 (free acid) |
| Molecular Formula | C10H10FN2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 248.19 g/mol gives Flumazenil Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Flumazenil Impurity 11 (CAS 1248271-71-7 (free acid), C10H10FN2O3Na) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H10FN2O3Na, Flumazenil Impurity 11 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 248.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Flumazenil Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10FN2O3 Na |
| Molecular Weight | 248.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Flumazenil Standards
- Flumazenil Impurity 17 (CAS 116569-09-6)
- Flumazenil EP Impurity C (CAS 1188-33-6)
- Flumazenil Impurity 14 (CAS 1291916-17-0)
- Flumazenil EP Impurity B (CAS 131666-45-0)
- Flumazenil Impurity 10 (CAS 162110-24-9)
- Flumazenil Impurity 22 (CAS 193693-31-1)
- Flumazenil-D5 (CAS 2700278-14-2)
- Flumazenil Impurity 19 (CAS 548487-68-9)
Recommended Standards
- Fosfomycin Impurity 51 Disodium Salt (CAS 76274-77-6(free base))
- Indometacin Impurity 37 (CAS CATO-C4X-147037)
- Granisetron EP Impurity E (CAS 76272-56-5)
- 3-Butoxybenzenethiol (CAS 1227191-83-4)
- (3r,4s)-1-(Tert-butoxycarbonyl)-4-(2-hydroxyphenyl)pyrrolidine-3-carboxylic acid (CAS 1392212-25-7)
- 4-Bromo-3-oxo-2,3-dihydro-1H-indazole-5-carbonitrile (CAS 2756657-93-7)
- 2-(Pyridin-3-ylmethyl)cyclopentan-1-ol (CAS 1501074-89-0)
- 2,4-Diethyl 5-amino-3-(bromomethyl)thiophene-2,4-dicarboxylate (CAS 132651-46-8)
- 2-Hydroxyhexanedioic Acid (CAS 18294-85-4)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com